Vacuolar protein sorting-associated protein 26B…

About Vacuolar protein sorting-associated protein 26B

Vacuolar protein sorting-associated protein 26B (VPS26B) is a protein from Homo sapiens identified by UniProt accession Q4G0F5, 336 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Vacuolar protein sorting-associated protein 26B
UniProt accession	Q4G0F5
Gene	VPS26B
Organism	Homo sapiens
Length	336 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.46
blood protein measurement · score 0.08
body mass index · score 0.04
body fat percentage · score 0.04
schizophrenia · score 0.04
fat body mass · score 0.04
alkaline phosphatase measurement · score 0.03
body weight · score 0.03
body height · score 0.03
protein measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q4G0F5-F1	alphafold	PREDICTED	86.51	—

Amino-acid sequence (336 residues)

MSFFGFGQSV EVEILLNDAE SRKRAEHKTE DGKKEKYFLF YDGETVSGKV SLALKNPNKR LEHQGIKIEF IGQIELYYDR GNHHEFVSLV KDLARPGEIT QSQAFDFEFT HVEKPYESYT GQNVKLRYFL RATISRRLND VVKEMDIVVH TLSTYPELNS SIKMEVGIED CLHIEFEYNK SKYHLKDVIV GKIYFLLVRI KIKHMEIDII KRETTGTGPN VYHENDTIAK YEIMDGAPVR GESIPIRLFL AGYELTPTMR DINKKFSVRY YLNLVLIDEE ERRYFKQQEV VLWRKGDIVR KSMSHQAAIA SQRFEGTTSL GEVRTPSQLS DNNCRQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Vacuolar protein sorting-associated protein 26B (VPS26B)