About Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 (NKAIN1) is a protein
from Homo sapiens identified by UniProt accession
Q4KMZ8, 207 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 |
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| UniProt accession | Q4KMZ8 |
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| Gene | NKAIN1 |
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| Organism | Homo sapiens |
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| Length | 207 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (22)
Diseases linked to this target (Open Targets).
- blood urea nitrogen measurement · score 0.29
- cystatin C measurement · score 0.20
- hematocrit · score 0.16
- hemoglobin measurement · score 0.11
- erythrocyte count · score 0.10
- red blood cell density measurement · score 0.10
- serum urea measurement · score 0.09
- alcohol dependence · score 0.09
- creatinine measurement · score 0.09
- mean corpuscular hemoglobin concentration · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q4KMZ8-F1 | alphafold | PREDICTED | 75.53 | — |
Amino-acid sequence (207 residues)
MGKCSGRCTL VAFCCLQLVA ALERQIFDFL GYQWAPILAN FLHIMAVILG IFGTVQYRSR YLILYAAWLV LWVGWNAFII CFYLEVGQLS QDRDFIMTFN TSLHRSWWME NGPGCLVTPV LNSRLALEDH HVISVTGCLL DYPYIEALSS ALQIFLALFG FVFACYVSKV FLEEEDSFDF IGGFDSYGYQ APQKTSHLQL QPLYTSG
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