About Testis-expressed protein 44
Testis-expressed protein 44 (TEX44) is a protein
from Homo sapiens identified by UniProt accession
Q53QW1, 395 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Testis-expressed protein 44 |
|---|
| UniProt accession | Q53QW1 |
|---|
| Gene | TEX44 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 395 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- bone density · score 0.29
- urate measurement · score 0.29
- adolescent idiopathic scoliosis · score 0.28
- mean platelet volume · score 0.28
- intelligence · score 0.22
- calcium measurement · score 0.02
- body height · score 0.02
- Abnormal sperm morphology · score 0.01
- papillary thyroid carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q53QW1-F1 | alphafold | PREDICTED | 47.40 | — |
Amino-acid sequence (395 residues)
MALPGYPLGN VDDSRSKDSP AGEPQGQVPL TADVLAVSSS VASTDWQDID QASFKTATPR AISTSGDKDK SAVVPEHGQK TPRKITPLLP SQNPSPLQVS MSLQNPAWDR QVQDARTSQS LVVFPSHLLG KDKMSQMASV PEREPESAPS APSAELQSTQ HMEAQPVESD ADHVTAGANG QHGPQAASTT KSAEEKAEHP KAPHPEAEAL PSDESPVAMG ANVVDSLGDL QTWFFPPPPA GSVSPSPGPH EVALGRRPLD SSLYTASEEN SYMRSMTSLL DRGEGSISSL ADILVWSETT MGMAIATGFL DSGHSTVADL LHSSGPSLRS VPSLVGSVSS AFSSGLVSGT SSALRTITRV LETVEQRTVE GIRSAMRYLT SHLTPRQAQA DPNYD
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