About BolA-like protein 3
BolA-like protein 3 (BOLA3) is a protein
from Homo sapiens identified by UniProt accession
Q53S33, 107 residues long.
MolForge cross-references it against 0 known binders and
45 disease associations.
Target properties
| Protein name | BolA-like protein 3 |
|---|
| UniProt accession | Q53S33 |
|---|
| Gene | BOLA3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 107 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (45)
Diseases linked to this target (Open Targets).
- multiple mitochondrial dysfunctions syndrome 2 · score 0.81
- Fatal multiple mitochondrial dysfunction syndrome · score 0.72
- Fatal multiple mitochondrial dysfunction syndrome type 2 · score 0.72
- fatal multiple mitochondrial dysfunctions syndrome · score 0.51
- mitochondrial disease · score 0.37
- mammographic density measurement · score 0.20
- genetic disorder · score 0.18
- risk-taking behaviour · score 0.09
- alcohol consumption measurement · score 0.09
- substance abuse · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q53S33-F1 | alphafold | PREDICTED | 80.97 | — |
Amino-acid sequence (107 residues)
MAAWSPAAAA PLLRGIRGLP LHHRMFATQT EGELRVTQIL KEKFPRATAI KVTDISGGCG AMYEIKIESE EFKEKRTVQQ HQMVNQALKE EIKEMHGLRI FTSVPKR
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