RILP-like protein 1 (RILPL1)

About RILP-like protein 1

RILP-like protein 1 (RILPL1) is a protein from Homo sapiens identified by UniProt accession Q5EBL4, 403 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	RILP-like protein 1
UniProt accession	Q5EBL4
Gene	RILPL1
Organism	Homo sapiens
Length	403 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

oculopharyngodistal myopathy · score 0.46
leukocyte count · score 0.25
neurodegenerative disease · score 0.25
triglyceride measurement · score 0.24
urate measurement · score 0.15
MODY · score 0.06
hyperproinsulinemia · score 0.04
lymphocyte count · score 0.04
Glycogen storage disease due to hepatic glycogen synthase deficiency · score 0.04
glycogen storage disorder due to hepatic glycogen synthase deficiency · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5EBL4-F1	alphafold	PREDICTED	75.94	—

Amino-acid sequence (403 residues)

MEEERGSALA AESALEKNVA ELTVMDVYDI ASLVGHEFER VIDQHGCEAI ARLMPKVVRV LEILEVLVSR HHVAPELDEL RLELDRLRLE RMDRIEKERK HQKELELVED VWRGEAQDLL SQIAQLQEEN KQLMTNLSHK DVNFSEEEFQ KHEGMSERER QVMKKLKEVV DKQRDEIRAK DRELGLKNED VEALQQQQTR LMKINHDLRH RVTVVEAQGK ALIEQKVELE ADLQTKEQEM GSLRAELGKL RERLQGEHSQ NGEEEPETEP VGEESISDAE KVAMDLKDPN RPRFTLQELR DVLHERNELK SKVFLLQEEL AYYKSEEMEE ENRIPQPPPI AHPRTSPQPE SGIKRLFSFF SRDKKRLANT QRNVHIQESF GQWANTHRDD GYTEQGQEAL QHL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards