About XK-related protein 7
XK-related protein 7 (XKR7) is a protein
from Homo sapiens identified by UniProt accession
Q5GH72, 579 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | XK-related protein 7 |
|---|
| UniProt accession | Q5GH72 |
|---|
| Gene | XKR7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 579 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- metabolite measurement · score 0.15
- drug use measurement · score 0.06
- Familial exudative vitreoretinopathy · score 0.04
- proliferative vitreoretinopathy · score 0.04
- exudative vitreoretinopathy 2, X-linked · score 0.03
- monocyte percentage of leukocytes · score 0.03
- Ataxia-telangiectasia · score 0.03
- breast carcinoma · score 0.03
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5GH72-F1 | alphafold | PREDICTED | 67.41 | — |
Amino-acid sequence (579 residues)
MAAKSDGAAA SASPDPEGAA GGARGSAGGR GEAAAAAGPP GVVGAGGPGP RYELRDCCWV LCALLVFFSD GATDLWLAAS YYLQNQHTYF SLTLLFVLLP SLVVQLLSFR WFVYDYSEPA GSPGPAVSTK DSVAGGAAIS TKDSAGAFRT KEGSPEPGPQ PAPSSASAYR RRCCRLCIWL LQTLVHLLQL GQVWRYLRAL YLGLQSRWRG ERLRRHFYWQ MLFESADVSM LRLLETFLRS APQLVLQLSL LVHRGGAPDL LPALSTSASL VSLAWTLASY QKVLRDSRDD KRPLSYKGAV AQVLWHLFSI AARGLAFALF ASVYKLYFGI FIVAHWCVMT FWVIQGETDF CMSKWEEIIY NMVVGIIYIF CWFNVKEGRS RRRMTLYHCI VLLENAALTG FWYSSRNFST DFYSLIMVCV VASSFALGIF FMCVYYCLLH PNGPMLGPQA PGCIFRKASE PCGPPADAIT SPPRSLPRTT GAERDGASAG ERAGTPTPPV FQVRPGLPPT PVARTLRTEG PVIRIDLPRK KYPAWDAHFI DRRLRKTILA LEYSSPATPR LQYRSVGTSQ ELLEYETTV
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