About Protein FAM47A
Protein FAM47A (FAM47A) is a protein
from Homo sapiens identified by UniProt accession
Q5JRC9, 791 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Protein FAM47A |
|---|
| UniProt accession | Q5JRC9 |
|---|
| Gene | FAM47A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 791 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- Abnormality of neuronal migration · score 0.11
- testosterone measurement · score 0.09
- self reported educational attainment · score 0.03
- carcinoma of liver and intrahepatic biliary tract · score 0.02
- breast carcinoma · score 0.01
- lung adenocarcinoma · score 0.01
- central congenital hypothyroidism · score 0.00
- hepatocellular carcinoma · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5JRC9-F1 | alphafold | PREDICTED | 47.24 | — |
Amino-acid sequence (791 residues)
MGDQRLQDWL RSPGMDSKPW YCNKRPSKCF AKCKHRRLRF PPMDTQNWVF VKEGMDDFRY GCPSPEDTLV CRRDEFLLPK ISLRGPQADP KSGQKKLLKK AALFSKLSPA QLARKAFVEQ VEAQLMAKHP LAMYPNLGED MPPDLLLQVL KHLDPERELE DAWACCETQE KTTEVPTEPG KHPCGEFCLK PPETPVSHLL PEPPETGVSH LSPEPPKTPV SSLRPEPPET GVSHLRPEPP ETGVSHIRPG PPITRRRSSL LRQLLKLDSE RKLEDARAPC EGREKTTDEP TEPGKYPCGK FCPRPFETPL SHLRQEPPKT PVSSLRPEPP ETGESHLRLE HSKTRRGSSL RSEPSETGVS RLRLAPPKTR RGSSLHAEPS KTGVSHLSPE PPKTEVSHLH PVPPKTGVCH LRLEPPDTSQ VSNLLLYILK VLDSGRTLKD VWDRCEARVK KTKEPTEPHK SPCGEPCLQP PETQVSHPHP EHPKTRRRSS LHSQPPKTRR TSSLRSEPPK TRRTSSLRSE PPKTRRTSSL GPEPPKTRRV SSLRPELPKS RRVSSLHPEP PKAPESHQFS EPPKIRASYI KELLQEDTPS TKECVSDSLQ YRYTSEKLRE FFKWAGDLGA DEESIRNLFD FTPKYRATHE DQKFKKVKEC SSELKYSMEL DEKDEDKFFS QEKYWGRKFH TPSNSYTAQR VKMKYGAWYL KPKLWKKLRS DEPLIDPKLL LKKPDEPDVL DDLYGPIAFK DFILSKGYEM PGIIQRLFAR RGWTYDSVKT PIQRAMIFYK YKEIVEASEE D
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