Solute carrier family 35 member D3 (SLC35D3)

About Solute carrier family 35 member D3

Solute carrier family 35 member D3 (SLC35D3) is a protein from Homo sapiens identified by UniProt accession Q5M8T2, 416 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein name	Solute carrier family 35 member D3
UniProt accession	Q5M8T2
Gene	SLC35D3
Organism	Homo sapiens
Length	416 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (33)

Diseases linked to this target (Open Targets).

calcium measurement · score 0.43
blood phosphate measurement · score 0.39
glucose measurement · score 0.33
neurodegenerative disease · score 0.32
type 2 diabetes mellitus · score 0.24
Drugs used in diabetes use measurement · score 0.16
hemoglobin A1 measurement · score 0.13
HbA1c measurement · score 0.13
lymphocyte percentage of leukocytes · score 0.10
Obesity · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5M8T2-F1	alphafold	PREDICTED	76.59	—

Amino-acid sequence (416 residues)

MRQLCRGRVL GISVAIAHGV FSGSLNILLK FLISRYQFSF LTLVQCLTSS TAALSLELLR RLGLIAVPPF GLSLARSFAG VAVLSTLQSS LTLWSLRGLS LPMYVVFKRC LPLVTMLIGV LVLKNGAPSP GVLAAVLITT CGAALAGAGD LTGDPIGYVT GVLAVLVHAA YLVLIQKASA DTEHGPLTAQ YVIAVSATPL LVICSFASTD SIHAWTFPGW KDPAMVCIFV ACILIGCAMN FTTLHCTYIN SAVTTSFVGV VKSIATITVG MVAFSDVEPT SLFIAGVVVN TLGSIIYCVA KFMETRKQSN YEDLEAQPRG EEAQLSGDQL PFVMEELPGE GGNGRSEGGE AAGGPAQESR QEVRGSPRGV PLVAGSSEEG SRRSLKDAYL EVWRLVRGTR YMKKDYLIEN EELPSP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards