About Transmembrane protein 201
Transmembrane protein 201 (TMEM201) is a protein
from Homo sapiens identified by UniProt accession
Q5SNT2, 666 residues long.
MolForge cross-references it against 0 known binders and
72 disease associations.
Target properties
| Protein name | Transmembrane protein 201 |
|---|
| UniProt accession | Q5SNT2 |
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| Gene | TMEM201 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 666 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (72)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.41
- drug use measurement · score 0.08
- FEV/FVC ratio · score 0.06
- body height · score 0.05
- hepatocellular carcinoma · score 0.05
- Inguinal hernia · score 0.04
- Hernia · score 0.04
- appendicular lean mass · score 0.04
- glomerulosclerosis · score 0.04
- neoplasm · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5SNT2-F1 | alphafold | PREDICTED | 58.70 | — |
Amino-acid sequence (666 residues)
MEGVSALLAR CPTAGLAGGL GVTACAAAGV LLYRIARRMK PTHTMVNCWF CNQDTLVPYG NRNCWDCPHC EQYNGFQENG DYNKPIPAQY LEHLNHVVSS APSLRDPSQP QQWVSSQVLL CKRCNHHQTT KIKQLAAFAP REEGRYDEEV EVYRHHLEQM YKLCRPCQAA VEYYIKHQNR QLRALLLSHQ FKRREADQTH AQNFSSAVKS PVQVILLRAL AFLACAFLLT TALYGASGHF APGTTVPLAL PPGGNGSATP DNGTTPGAEG WRQLLGLLPE HMAEKLCEAW AFGQSHQTGV VALGLLTCLL AMLLAGRIRL RRIDAFCTCL WALLLGLHLA EQHLQAASPS WLDTLKFSTT SLCCLVGFTA AVATRKATGP RRFRPRRFFP GDSAGLFPTS PSLAIPHPSV GGSPASLFIP SPPSFLPLAN QQLFRSPRRT SPSSLPGRLS RALSLGTIPS LTRADSGYLF SGSRPPSQVS RSGEFPVSDY FSLLSGSCPS SPLPSPAPSV AGSVASSSGS LRHRRPLISP ARLNLKGQKL LLFPSPPGEA PTTPSSSDEH SPHNGSLFTM EPPHVPRKPP LQDVKHALDL RSKLERGSAC SNRSIKKEDD SSQSSTCVVD TTTRGCSEEA ATWRGRFGPS LVRGLLAVSL AANALFTSVF LYQSLR
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