Suppressor APC domain-containing protein 1 (SAPCD1)

About Suppressor APC domain-containing protein 1

Suppressor APC domain-containing protein 1 (SAPCD1) is a protein from Homo sapiens identified by UniProt accession Q5SSQ6, 148 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	Suppressor APC domain-containing protein 1
UniProt accession	Q5SSQ6
Gene	SAPCD1
Organism	Homo sapiens
Length	148 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

lymphocyte count · score 0.12
age at menopause · score 0.08
complement C4 measurement · score 0.08
pulse pressure measurement · score 0.07
melorheostosis · score 0.06
dacryocystitis-osteopoikilosis syndrome · score 0.06
12q14 microdeletion syndrome · score 0.06
osteoporosis · score 0.05
Osteoporosis · score 0.05
pyknoachondrogenesis · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5SSQ6-F1	alphafold	PREDICTED	74.63	—

Amino-acid sequence (148 residues)

MGSQGSGGVP LVQAPYTVLL LPLGTSRQDP GAQSFFLWLR RMQALEREQD ALWQGLELLQ HGQAWFEDHL REAQRQQLHL GALGENFLTD LHSEPGRPPL AQIQKVNICL QNLIHEKELS RQQKGVTQPK EEMAQRGCTK GPRGPTRV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards