About Uncharacterized protein C9orf50
Uncharacterized protein C9orf50 (C9orf50) is a protein
from Homo sapiens identified by UniProt accession
Q5SZB4, 431 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Uncharacterized protein C9orf50 |
|---|
| UniProt accession | Q5SZB4 |
|---|
| Gene | C9orf50 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 431 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- body height · score 0.24
- neurodegenerative disease · score 0.23
- serum alanine aminotransferase measurement · score 0.19
- sitting height measurement · score 0.16
- arterial stiffness measurement · score 0.12
- chronotype measurement · score 0.08
- protein measurement · score 0.06
- body fat percentage · score 0.05
- atopic eczema · score 0.04
- fat body mass · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5SZB4-F1 | alphafold | PREDICTED | 44.12 | — |
Amino-acid sequence (431 residues)
MFWRRLRPGA QDLAPKGLPG DGDFRRSSDP RLPKLTPPAL RAALGARGSG DWRIPGGGAA WWPEGDAKPG VGVGRLPPRL PALLTATRRA VRKRGLLRSL LPPPLLSAGA SRESAPRQPG PGERERPRRR VAREDPDFLG AFLGELLPSR FREFLHQLQE KCAEEPEPLT SPAPQHQRGV LEHCPGSPRC PNCSFLPDLW GQSSHLQDSL TKISLQQTPI LGPLKGDHSQ FTTVRKANHR PHGAQVPRLK AALTHNPSGE GSRPCRQRCP FRVRFADETL QDTTLRYWER RRSVQQSVIV NQKAALPVAS ERVFGSVGKR LESLPKALYP GAKEETLASS SCWDCAGLST QKTQGYLSED TSMNSSLPFC SWKKAAAQRP RSSLRAFLDP HRNLEQESLL PNRVLQSVLK QGCPKGYHLL LASATLQPDK R
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