MORN repeat-containing protein 1 (MORN1)

About MORN repeat-containing protein 1

MORN repeat-containing protein 1 (MORN1) is a protein from Homo sapiens identified by UniProt accession Q5T089, 497 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein name	MORN repeat-containing protein 1
UniProt accession	Q5T089
Gene	MORN1
Organism	Homo sapiens
Length	497 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (33)

Diseases linked to this target (Open Targets).

mean corpuscular volume · score 0.35
mean corpuscular hemoglobin concentration · score 0.34
mean corpuscular hemoglobin · score 0.31
protein measurement · score 0.26
neurodegenerative disease · score 0.24
erythrocyte count · score 0.24
HMG CoA reductase inhibitor use measurement · score 0.23
systolic blood pressure · score 0.23
coronary artery disease · score 0.20
body height · score 0.17

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5T089-F1	alphafold	PREDICTED	74.55	—

Amino-acid sequence (497 residues)

MAAAGEGTPS SRGPRRDPPR RPPRNGYGVY VYPNSFFRYE GEWKAGRKHG HGKLLFKDGS YYEGAFVDGE ITGEGRRHWA WSGDTFSGQF VLGEPQGYGV MEYKAGGCYE GEVSHGMREG HGFLVDRDGQ VYQGSFHDNK RHGPGQMLFQ NGDKYDGDWV RDRRQGHGVL RCADGSTYKG QWHSDVFSGL GSMAHCSGVT YYGLWINGHP AEQATRIVIL GPEVMEVAQG SPFSVNVQLL QDHGEIAKSE SGRVLQISAG VRYVQLSAYS EVNFFKVDRD NQETLIQTPF GFECIPYPVS SPAAGVPGPR AAKGGAEADV PLPRGDLELH LGALHGQEDT PGGLLARGHA PHCPGACQRV EQGCAEFTDV LLGPPPPGYH PFLFLDSLHK KAGGRSRGGL HPRGTPPTAQ EPPGGSRPEG RATEEQAAAA HLGEYVLMIR DVTTPPFLGR RLPPAFKHLR VVAKRAGQPP HVLEEGPEAS SSWQAAHSCT PEPPAPR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards