UBX domain-containing protein 11 (UBXN11)

About UBX domain-containing protein 11

UBX domain-containing protein 11 (UBXN11) is a protein from Homo sapiens identified by UniProt accession Q5T124, 520 residues long. MolForge cross-references it against 0 known binders and 341 disease associations.

Target properties

Protein name	UBX domain-containing protein 11
UniProt accession	Q5T124
Gene	UBXN11
Organism	Homo sapiens
Length	520 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (341)

Diseases linked to this target (Open Targets).

eosinophil count · score 0.29
monocyte count · score 0.28
monocyte percentage of leukocytes · score 0.25
glioblastoma multiforme · score 0.22
platelet count · score 0.21
brain measurement · score 0.16
lymphocyte:monocyte ratio · score 0.15
lymphocyte count · score 0.13
eosinophil percentage of leukocytes · score 0.12
PR interval · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5T124-F1	alphafold	PREDICTED	71.58	—

Amino-acid sequence (520 residues)

MSSPLASLSK TRKVPLPSEP MNPGRRGIRI YGDEDEVDML SDGCGSEEKI SVPSCYGGIG APVSRQVPAS HDSELMAFMT RKLWDLEQQV KAQTDEILSK DQKIAALEDL VQTLRPHPAE ATLQRQEELE TMCVQLQRQV REMERFLSDY GLQWVGEPMD QEDSESKTVS EHGERDWMTA KKFWKPGDSL APPEVDFDRL LASLQDLSEL VVEGDTQVTP VPGGARLRTL EPIPLKLYRN GIMMFDGPFQ PFYDPSTQRC LRDILDGFFP SELQRLYPNG VPFKVSDLRN QVYLEDGLDP FPGEGRVVGR QLMHKALDRV EEHPGSRMTA EKFLNRLPKF VIRQGEVIDI RGPIRDTLQN CCPLPARIQE IVVETPTLAA ERERSQESPN TPAPPLSMLR IKSENGEQAF LLMMQPDNTI GDVRALLAQA RVMDASAFEI FSTFPPTLYQ DDTLTLQAAG LVPKAALLLR ARRAPKSSLK FSPGPCPGPG PGPSPGPGPG PSPGPGPGPS PCPGPSPSPQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards