Large ribosomal subunit protein uL2m (MRPL2)

About Large ribosomal subunit protein uL2m

Large ribosomal subunit protein uL2m (MRPL2) is a protein from Homo sapiens identified by UniProt accession Q5T653, 305 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Large ribosomal subunit protein uL2m
UniProt accession	Q5T653
Gene	MRPL2
Organism	Homo sapiens
Length	305 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.38
hemoglobin measurement · score 0.06
mean corpuscular hemoglobin concentration · score 0.03
infect · score 0.01
infection · score 0.01
systemic juvenile idiopathic arthritis · score 0.01
neoplasm · score 0.00
unipolar depression · score 0.00
Gaucher disease type 1 · score 0.00
hyperopia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5T653-F1	alphafold	PREDICTED	85.35	—

Amino-acid sequence (305 residues)

MALCALTRAL RSLNLAPPTV AAPAPSLFPA AQMMNNGLLQ QPSALMLLPC RPVLTSVALN ANFVSWKSRT KYTITPVKMR KSGGRDHTGR IRVHGIGGGH KQRYRMIDFL RFRPEETKSG PFEEKVIQVR YDPCRSADIA LVAGGSRKRW IIATENMQAG DTILNSNHIG RMAVAAREGD AHPLGALPVG TLINNVESEP GRGAQYIRAA GTCGVLLRKV NGTAIIQLPS KRQMQVLETC VATVGRVSNV DHNKRVIGKA GRNRWLGKRP NSGRWHRKGG WAGRKIRPLP PMKSYVKLPS ASAQS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards