Protein lin-9 homolog (LIN9)

About Protein lin-9 homolog

Protein lin-9 homolog (LIN9) is a protein from Homo sapiens identified by UniProt accession Q5TKA1, 542 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.

Target properties

Protein name	Protein lin-9 homolog
UniProt accession	Q5TKA1
Gene	LIN9
Organism	Homo sapiens
Length	542 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (69)

Diseases linked to this target (Open Targets).

ovarian cancer · score 0.23
breast adenocarcinoma · score 0.23
mean platelet volume · score 0.18
endometrial cancer · score 0.16
mean corpuscular hemoglobin concentration · score 0.15
Red cell distribution width · score 0.14
sex hormone-binding globulin measurement · score 0.13
mean corpuscular volume · score 0.13
mean corpuscular hemoglobin · score 0.11
myeloid white cell count · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5TKA1-F1	alphafold	PREDICTED	70.81	—

Amino-acid sequence (542 residues)

MAELDQLPDE SSSAKALVSL KEGSLSNTWN EKYSSLQKTP VWKGRNTSSA VEMPFRNSKR SRLFSDEDDR QINTRSPKRN QRVAMVPQKF TATMSTPDKK ASQKIGFRLR NLLKLPKAHK WCIYEWFYSN IDKPLFEGDN DFCVCLKESF PNLKTRKLTR VEWGKIRRLM GKPRRCSSAF FEEERSALKQ KRQKIRLLQQ RKVADVSQFK DLPDEIPLPL VIGTKVTARL RGVHDGLFTG QIDAVDTLNA TYRVTFDRTG LGTHTIPDYE VLSNEPHETM PIAAFGQKQR PSRFFMTPPR LHYTPPLQSP IIDNDPLLGQ SPWRSKISGS DTETLGGFPV EFLIQVTRLS KILMIKKEHI KKLREMNTEA EKLKSYSMPI SIEFQRRYAT IVLELEQLNK DLNKVLHKVQ QYCYELAPDQ GLQPADQPTD MRRRCEEEAQ EIVRHANSST GQPCVENENL TDLISRLTAI LLQIKCLAEG GDLNSFEFKS LTDSLNDIKS TIDASNISCF QNNVEIHVAH IQSGLSQMGN LHAFAANNTN RD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards