About Protein FAM171A1
Protein FAM171A1 (FAM171A1) is a protein
from Homo sapiens identified by UniProt accession
Q5VUB5, 890 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | Protein FAM171A1 |
|---|
| UniProt accession | Q5VUB5 |
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| Gene | FAM171A1 |
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| Organism | Homo sapiens |
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| Length | 890 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (43)
Diseases linked to this target (Open Targets).
- diffuse plaque measurement · score 0.22
- visual perception measurement · score 0.15
- peak expiratory flow · score 0.12
- triple-negative breast cancer · score 0.08
- Parkinson disease · score 0.06
- BMI-adjusted hip circumference · score 0.03
- neoplasm · score 0.03
- mean reticulocyte volume · score 0.02
- FEV/FVC ratio · score 0.02
- chronic kidney disease · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5VUB5-F1 | alphafold | PREDICTED | 57.12 | — |
Amino-acid sequence (890 residues)
MSRSATLLLC LLGCHVWKAV TKTLREPGAG AQEVTLKVHI SDASTHQPVA DALIEIFTNQ ASIASGTSGT DGVAFIKFQY KLGSQLIVTA SKHAYVPNSA PWKPIRLPVF SSLSLGLLPE RSATLMVYED VVQIVSGFQG ARPQPRVHFQ RRALRLPENT SYSDLTAFLT AASSPSEVDS FPYLRGLDGN GTGNSTRHDL TPVTAVSVHL LSSNGTPVLV DGPIYVTVPL ATQSSLRHNA YVAAWRFDQK LGTWLKSGLG LVHQEGSQLT WTYIAPQLGY WVAAMSPPIP GPVVTQDITT YHTVFLLAIL GGMAFILLVL LCLLLYYCRR KCLKPRQHHR KLQLPAGLES SKRDQSTSMS HINLLFSRRA SEFPGPLSVT SHGRPEAPGT KELMSGVHLE MMSPGGEGDL HTPMLKLSYS TSQEFSSREE LLSCKEEDKS QISFDNLTPS GTLGKDYHKS VEVFPLKARK SMEREGYESS GNDDYRGSYN TVLSQPLFEK QDREGPASTG SKLTIQEHLY PAPSSPEKEQ LLDRRPTECM MSRSVDHLER PTSFPRPGQL ICCSSVDQVN DSVYRKVLPA LVIPAHYMKL PGDHSYVSQP LVVPADQQLE IERLQAELSN PHAGIFPHPS SQIQPQPLSS QAISQQHLQD AGTREWSPQN ASMSESLSIP ASLNDAALAQ MNSEVQLLTE KALMELGGGK PLPHPRAWFV SLDGRSNAHV RHSYIDLQRA GRNGSNDASL DSGVDMNEPK SARKGRGDAL SLQQNYPPVQ EHQQKEPRAP DSTAYTQLVY LDDVEQSGSE CGTTVCTPED SALRCLLEGS SRRSGGQLPS LQEETTRRTA DAPSEPAASP HQRRSAHEEE EDDDDDDQGE DKKSPWQKRE ERPLMAFNIK
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