Putative transmembrane protein 244 (TMEM244)

About Putative transmembrane protein 244

Putative transmembrane protein 244 (TMEM244) is a protein from Homo sapiens identified by UniProt accession Q5VVB8, 128 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Putative transmembrane protein 244
UniProt accession	Q5VVB8
Gene	TMEM244
Organism	Homo sapiens
Length	128 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

body fat percentage · score 0.25
fat body mass · score 0.16
type 2 diabetes mellitus · score 0.14
heel bone mineral density · score 0.03
Cutaneous T-cell lymphoma · score 0.03
Headache · score 0.03
Abdominal pain · score 0.03
Limb pain · score 0.03
body height · score 0.02
acute lymphoblastic leukemia · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5VVB8-F1	alphafold	PREDICTED	84.31	—

Amino-acid sequence (128 residues)

MALQVRVAPS KVVLQKFLLC VILFYTVYYV SLSMGCVMFE VHELNVLAPF DFKTNPSWLN INYKVLLVST EVTYFVCGLF FVPVVEEWVW DYAISVTILH VAITSTVMLE FPLTSHWWAA LGISKLLV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards