About Protein SPO16 homolog
Protein SPO16 homolog (SPO16) is a protein
from Homo sapiens identified by UniProt accession
Q5VVC0, 180 residues long.
MolForge cross-references it against 0 known binders and
140 disease associations.
Target properties
| Protein name | Protein SPO16 homolog |
|---|
| UniProt accession | Q5VVC0 |
|---|
| Gene | SPO16 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 180 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (140)
Diseases linked to this target (Open Targets).
- monocyte percentage of leukocytes · score 0.34
- type 1 diabetes mellitus · score 0.20
- Red cell distribution width · score 0.13
- azoospermia · score 0.08
- testosterone measurement · score 0.08
- male infertility with teratozoospermia due to single gene mutation · score 0.07
- partial chromosome Y deletion · score 0.07
- serum alanine aminotransferase measurement · score 0.06
- total cholesterol measurement · score 0.06
- primary ovarian insufficiency · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5VVC0-F1 | alphafold | PREDICTED | 85.98 | — |
Amino-acid sequence (180 residues)
MAESGKEKIK WTTTIIISSS LKSYEVATAL ENRSHKVRYS DSVENGSIIF SLSGVAFLLM DTKECLLSTE EIFLAKIEKF INIHQNSFLV LSAALHGPEE WKLMFRIQQR FLGCNLRILP VHNTVNAINL MCTIAKTTSK PYIDSICYRM ITAKAYIIEQ SPVWKTLQKI KLNSDSVNPN
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