Complement C1q-like protein 3 (C1QL3)

About Complement C1q-like protein 3

Complement C1q-like protein 3 (C1QL3) is a protein from Homo sapiens identified by UniProt accession Q5VWW1, 255 residues long. MolForge cross-references it against 0 known binders and 131 disease associations.

Target properties

Protein name	Complement C1q-like protein 3
UniProt accession	Q5VWW1
Gene	C1QL3
Organism	Homo sapiens
Length	255 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (131)

Diseases linked to this target (Open Targets).

attention deficit hyperactivity disorder · score 0.09
PHF-tau measurement · score 0.08
type 2 diabetes mellitus · score 0.07
attention deficit-hyperactivity disorder 8 · score 0.07
Tourette syndrome · score 0.07
Potocki-Lupski syndrome · score 0.07
X-linked severe congenital neutropenia · score 0.06
non-alcoholic fatty liver disease · score 0.06
Blackfan-Diamond anemia · score 0.06
coronary artery disease · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5VWW1-F1	alphafold	PREDICTED	79.08	—

Amino-acid sequence (255 residues)

MVLLLVILIP VLVSSAGTSA HYEMLGTCRM VCDPYGGTKA PSTAATPDRG LMQSLPTFIQ GPKGEAGRPG KAGPRGPPGE PGPPGPMGPP GEKGEPGRQG LPGPPGAPGL NAAGAISAAT YSTVPKIAFY AGLKRQHEGY EVLKFDDVVT NLGNHYDPTT GKFTCSIPGI YFFTYHVLMR GGDGTSMWAD LCKNNQVRAS AIAQDADQNY DYASNSVVLH LEPGDEVYIK LDGGKAHGGN NNKYSTFSGF IIYAD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards