Uncharacterized protein KIAA1614 (KIAA1614)

About Uncharacterized protein KIAA1614

Uncharacterized protein KIAA1614 (KIAA1614) is a protein from Homo sapiens identified by UniProt accession Q5VZ46, 1190 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Uncharacterized protein KIAA1614
UniProt accession	Q5VZ46
Gene	KIAA1614
Organism	Homo sapiens
Length	1190 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

lean body mass · score 0.46
monocyte count · score 0.45
platelet count · score 0.44
body height · score 0.44
alkaline phosphatase measurement · score 0.43
leukocyte count · score 0.43
glomerular filtration rate · score 0.41
creatinine measurement · score 0.38
cortical surface area measurement · score 0.38
myeloid white cell count · score 0.38

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5VZ46-F1	alphafold	PREDICTED	42.51	—

Amino-acid sequence (1190 residues)

MEGTEAAAAK PAGGSPQGPK TGSGTASPVE GTSAVEWSGP EPQLDNGHPP RPWPCPQENR TSSLMAPQPP RVWGVQLQGP SVLESKVRAL KEKMTVAKQG VSPCSASQEW SSPKKPQCRR GKAGRAGTPS EGSFLPGAVV APRTQNLPDG QLDGSINEEQ PARDGGPRLP RPPAPGREYC NRGSPWPPEA EWTLPDHDRG PLLGPSSLQQ SPIHGVTPGR PGGPGHCNKI IHIPSPRTGR SYPFPDGVVT EADLDSTSLT SEEVFVPRTA LLGERWRAGD LEALGAGSSV LSLSDRVERN RLLLQEMLNV SGQSPRKVGT PAWTPSWDTA APERPVGDVD WASGTSLQDS GQNRTVGPNP EPVLSPRHEE ATHLLQRARM KARTRPLRAS HDIVPTITQG SRDGHRSPAR DPRTTPACRD SLQNGHTSDS SSGESSGGHR PRRGPSPSHV RFEDESAREA EFRHLERLQQ RQRQVLSTVL QAADQGPLRS KPDLADYING APRLRDAGQG TFHRLVGSLD RRGHPAPPAP GSERRCQACG SCIDDPRPAQ GKAPPVPRTL QELQAACGME RVLGGLSSPL RLLPAEPRLH MEWIRETHIG DTVCPAEVDS ALDSTDNSDN CRTDSEEAGT SQAGWACGRT QGSSPRLRLR GSRPRGHRWS KKAEAELPWG LQAQQHLPRA DDVEVENEVK EGRGHTPEGT LFLREDAKPP DLELKRVSLG PQWQPGPGLG SHQPHPLDSR TPCRTAYATT APMTPESSGP GGQAQVTESH ESLEIVSPSS LQQSHAEPSA PHQAWQPTAS LCPEGWAPTP PPSRKTTSPV SHRKAALAGL LRLGDQTEPV GIPRPPSRSA VLRTCELPPS QTQPSRPQVR HPLLALSTNN CNNSAPRGLQ EPYGGAVHEG RVERGPCSRE PEPPLENSRD GGPQGFLGSA DVATINSTGI TLSLSSEESE SSKESEGSLQ RTGSGSGGHV LSRASAGAGT GPGSPSAAPL DQNKKRSSSI ASTLGLKKLF SALGQSSRPK LGKSRSYSVE QLQPAPPGLT SQSRAPSLQS LHPVSPSHQR RKAASFQNLH SLLSSKGNRS SLYLVAGPGD HSAAGRPAKT SPRRALSVED VGAPSLARTV GRLVEVFPDG TSQLQLQRSP GGTFGFCVAS GNGRPDSGMP SPLPQPHGWG GLSKQGRAFW LWSEAFLVFG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards