About SPRY domain-containing protein 7
SPRY domain-containing protein 7 (SPRYD7) is a protein
from Homo sapiens identified by UniProt accession
Q5W111, 196 residues long.
MolForge cross-references it against 0 known binders and
63 disease associations.
Target properties
| Protein name | SPRY domain-containing protein 7 |
|---|
| UniProt accession | Q5W111 |
|---|
| Gene | SPRYD7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 196 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (63)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.26
- lymphocyte count · score 0.24
- body height · score 0.20
- sex hormone-binding globulin measurement · score 0.18
- waist-hip ratio · score 0.17
- heel bone mineral density · score 0.17
- body fat percentage · score 0.14
- monocyte percentage of leukocytes · score 0.13
- hypertension · score 0.11
- eosinophil count · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5W111-F1 | alphafold | PREDICTED | 89.95 | — |
Amino-acid sequence (196 residues)
MATSVLCCLR CCRDGGTGHI PLKEMPAVQL DTQHMGTDVV IVKNGRRICG TGGCLASAPL HQNKSYFEFK IQSTGIWGIG VATQKVNLNQ IPLGRDMHSL VMRNDGALYH NNEEKNRLPA NSLPQEGDVV GITYDHVELN VYLNGKNMHC PASGIRGTVY PVVYVDDSAI LDCQFSEFYH TPPPGFEKIL FEQQIF
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