LysM and putative peptidoglycan-binding…

About LysM and putative peptidoglycan-binding domain-containing protein 4

LysM and putative peptidoglycan-binding domain-containing protein 4 (LYSMD4) is a protein from Homo sapiens identified by UniProt accession Q5XG99, 296 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

Target properties

Protein name	LysM and putative peptidoglycan-binding domain-containing protein 4
UniProt accession	Q5XG99
Gene	LYSMD4
Organism	Homo sapiens
Length	296 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (18)

Diseases linked to this target (Open Targets).

vitamin D measurement · score 0.29
cranial vault morphology measurement · score 0.28
BMI-adjusted waist-hip ratio · score 0.21
mean arterial pressure · score 0.14
vital capacity · score 0.07
body height · score 0.06
systolic blood pressure · score 0.06
forced expiratory volume · score 0.05
body fat percentage · score 0.05
sitting height measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5XG99-F1	alphafold	PREDICTED	62.43	—

Amino-acid sequence (296 residues)

MRHEELLTKT FQGPAVVCGT PTSHVYMFKN GSGDSGDSSE EESHRVVLRP RGKERHKSGV HQPPQAGAGD VVLLQRELAQ EDSLNKLALQ YGCKVADIKK VNNFIREQDL YALKSVKIPV RNHGILMETH KELKPLLSPS SETTVTVELP EADRAGAGTG AQAGQLMGFF KGIDQDIERA VQSEIFLHES YCMDTSHQPL LPAPPKTPMD GADCGIQWWN AVFIMLLIGI VLPVFYLVYF KIQASGETPN SLNTTVIPNG SMAMGTVPGQ APRLAVAVPA VTSADSQFSQ TTQAGS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

LysM and putative peptidoglycan-binding domain-containing protein 4 (LYSMD4)