About Pikachurin
Pikachurin (EGFLAM) is a protein
from Homo sapiens identified by UniProt accession
Q63HQ2, 1017 residues long.
MolForge cross-references it against 0 known binders and
44 disease associations.
Target properties
| Protein name | Pikachurin |
|---|
| UniProt accession | Q63HQ2 |
|---|
| Gene | EGFLAM |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1017 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (44)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.36
- vital capacity · score 0.33
- self reported educational attainment · score 0.30
- protein measurement · score 0.25
- pathological myopia · score 0.11
- Myopia · score 0.11
- worry measurement · score 0.08
- glioblastoma multiforme · score 0.08
- bone density · score 0.02
- urate measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q63HQ2-F1 | alphafold | PREDICTED | 80.56 | — |
Amino-acid sequence (1017 residues)
MDLIRGVLLR LLLLASSLGP GAVSLRAAIR KPGKVGPPLD IKLGALNCTA FSIQWKMPRH PGSPILGYTV FYSEVGADKS LQEQLHSVPL SRDIPTTEEV IGDLKPGTEY RVSIAAYSQA GKGRLSSPRH VTTLSQDSCL PPAAPQQPHV IVVSDSEVAL SWKPGASEGS APIQYYSVEF IRPDFDKKWT SIHERIQMDS MVIKGLDPDT NYQFAVRAMN SHGPSPRSWP SDIIRTLCPE EAGSGRYGPR YITDMGAGED DEGFEDDLDL DISFEEVKPL PATKGGNKKF LVESKKMSIS NPKTISRLIP PTSASLPVTT VAPQPIPIQR KGKNGVAIMS RLFDMPCDET LCSADSFCVN DYTWGGSRCQ CTLGKGGESC SEDIVIQYPQ FFGHSYVTFE PLKNSYQAFQ ITLEFRAEAE DGLLLYCGEN EHGRGDFMSL AIIRRSLQFR FNCGTGVAII VSETKIKLGG WHTVMLYRDG LNGLLQLNNG TPVTGQSQGQ YSKITFRTPL YLGGAPSAYW LVRATGTNRG FQGCVQSLAV NGRRIDMRPW PLGKALSGAD VGECSSGICD EASCIHGGTC TAIKADSYIC LCPLGFKGRH CEDAFTLTIP QFRESLRSYA ATPWPLEPQH YLSFMEFEIT FRPDSGDGVL LYSYDTGSKD FLSINLAGGH VEFRFDCGSG TGVLRSEDPL TLGNWHELRV SRTAKNGILQ VDKQKIVEGM AEGGFTQIKC NTDIFIGGVP NYDDVKKNSG VLKPFSGSIQ KIILNDRTIH VKHDFTSGVN VENAAHPCVR APCAHGGSCR PRKEGYDCDC PLGFEGLHCQ KECGNYCLNT IIEAIEIPQF IGRSYLTYDN PDILKRVSGS RSNVFMRFKT TAKDGLLLWR GDSPMRPNSD FISLGLRDGA LVFSYNLGSG VASIMVNGSF NDGRWHRVKA VRDGQSGKIT VDDYGARTGK SPGMMRQLNI NGALYVGGMK EIALHTNRQY MRGLVGCISH FTLSTDYHIS LVEDAVDGKN INTCGAK
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