About Solute carrier family 22 member 10
Solute carrier family 22 member 10 (SLC22A10) is a protein
from Homo sapiens identified by UniProt accession
Q63ZE4, 541 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Target properties
| Protein name | Solute carrier family 22 member 10 |
|---|
| UniProt accession | Q63ZE4 |
|---|
| Gene | SLC22A10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 541 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (53)
Diseases linked to this target (Open Targets).
- pancreatic neoplasm · score 0.07
- hepatocellular carcinoma · score 0.06
- testosterone measurement · score 0.06
- hormone measurement · score 0.05
- progesterone measurement · score 0.05
- glycoprotein storage disease · score 0.05
- neuronal ceroid lipofuscinosis 1 · score 0.04
- neoplasm · score 0.04
- hemoglobin H disease · score 0.04
- hemoglobin C-beta-thalassemia syndrome · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q63ZE4-F1 | alphafold | PREDICTED | 87.33 | — |
Amino-acid sequence (541 residues)
MAFEELLSQV GGLGRFQMLH LVFILPSLML LIPHILLENF AAAIPGHRCW VHMLDNNTGS GNETGILSED ALLRISIPLD SNLRPEKCRR FVHPQWQLLH LNGTIHSTSE ADTEPCVDGW VYDQSYFPST IVTKWDLVCD YQSLKSVVQF LLLTGMLVGG IIGGHVSDRF GRRFILRWCL LQLAITDTCA AFAPTFPVYC VLRFLAGFSS MIIISNNSLP ITEWIRPNSK ALVVILSSGA LSIGQIILGG LAYVFRDWQT LHVVASVPFF VFFLLSRWLV ESARWLIITN KLDEGLKALR KVARTNGIKN AEETLNIEVV RSTMQEELDA AQTKTTVCDL FRNPSMRKRI CILVFLRFAN TIPFYGTMVN LQHVGSNIFL LQVLYGAVAL IVRCLALLTL NHMGRRISQI LFMFLVGLSI LANTFVPKEM QTLRVALACL GIGCSAATFS SVAVHFIELI PTVLRARASG IDLTASRIGA ALAPLLMTLT VFFTTLPWII YGIFPIIGGL IVFLLPETKN LPLPDTIKDV ENQKKNLKEK A
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