About Meteorin-like protein
Meteorin-like protein (METRNL) is a protein
from Homo sapiens identified by UniProt accession
Q641Q3, 311 residues long.
MolForge cross-references it against 0 known binders and
176 disease associations.
Target properties
| Protein name | Meteorin-like protein |
|---|
| UniProt accession | Q641Q3 |
|---|
| Gene | METRNL |
|---|
| Organism | Homo sapiens |
|---|
| Length | 311 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (176)
Diseases linked to this target (Open Targets).
- cataract · score 0.43
- hematocrit · score 0.41
- erythrocyte count · score 0.41
- monocyte count · score 0.40
- monocyte percentage of leukocytes · score 0.40
- hemoglobin measurement · score 0.38
- colorectal cancer · score 0.38
- eosinophil count · score 0.36
- leukocyte count · score 0.36
- red blood cell density measurement · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q641Q3-F1 | alphafold | PREDICTED | 83.66 | — |
Amino-acid sequence (311 residues)
MRGAARAAWG RAGQPWPRPP APGPPPPPLP LLLLLLAGLL GGAGAQYSSD RCSWKGSGLT HEAHRKEVEQ VYLRCAAGAV EWMYPTGALI VNLRPNTFSP ARHLTVCIRS FTDSSGANIY LEKTGELRLL VPDGDGRPGR VQCFGLEQGG LFVEATPQQD IGRRTTGFQY ELVRRHRASD LHELSAPCRP CSDTEVLLAV CTSDFAVRGS IQQVTHEPER QDSAIHLRVS RLYRQKSRVF EPVPEGDGHW QGRVRTLLEC GVRPGHGDFL FTGHMHFGEA RLGCAPRFKD FQRMYRDAQE RGLNPCEVGT D
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