About Protein FRG2
Protein FRG2 (FRG2) is a protein
from Homo sapiens identified by UniProt accession
Q64ET8, 278 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Protein FRG2 |
|---|
| UniProt accession | Q64ET8 |
|---|
| Gene | FRG2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 278 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- albuminuria · score 0.09
- urinary albumin to creatinine ratio · score 0.08
- triple-negative breast cancer · score 0.07
- urinary microalbumin measurement · score 0.07
- facioscapulohumeral muscular dystrophy · score 0.06
- Facioscapulohumeral dystrophy · score 0.05
- neoplasm · score 0.03
- cancer · score 0.01
- myopathy · score 0.00
- genetic disorder · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q64ET8-F1 | alphafold | PREDICTED | 60.03 | — |
Amino-acid sequence (278 residues)
MGKGNEDSDL HCSSIQCSTD QPPFQQISFT EKGSDEKKPF KEKGKTAFSH SSEKHIQRQG SEPNPNKENS EETKLKAGNS TAGSEPESSS YRENCRKRKM SSKDSCQDTA GNCPEKECSL SLNKKSRSST AVHNSEIQET CDAHHRGHSR ACTGHSKRHR SRALGVQTPS IRKSLVTSVR AMSEAVYQDL AQVWAQQIHS PLTCEQLTLL TRLRGPLCAQ VQTLYSMATQ AAYVFPAESW LVPATLPGPG ESALDREAHP FPGQEITETV SGSDEAKL
Explore Protein FRG2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets