About Olfactomedin-like protein 2B
Olfactomedin-like protein 2B (OLFML2B) is a protein
from Homo sapiens identified by UniProt accession
Q68BL8, 750 residues long.
MolForge cross-references it against 0 known binders and
74 disease associations.
Target properties
| Protein name | Olfactomedin-like protein 2B |
|---|
| UniProt accession | Q68BL8 |
|---|
| Gene | OLFML2B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 750 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (74)
Diseases linked to this target (Open Targets).
- electrocardiography · score 0.30
- C-reactive protein measurement · score 0.29
- neutrophil count · score 0.24
- leukocyte count · score 0.21
- blood protein measurement · score 0.14
- neoplasm · score 0.08
- QT interval · score 0.08
- cancer · score 0.08
- gonorrhea · score 0.08
- monocyte count · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q68BL8-F1 | alphafold | PREDICTED | 62.38 | — |
Amino-acid sequence (750 residues)
MAKPRLLVLY FALIVVPAWV SSIVLTGTSE PPDAQTVAPA EDETLQNEAD NQENVLSQLL GDYDKVKAMS EGSDCQCKCV VRPLGRDACQ RINAGASRKE DFYTVETITS GSSCKCACVA PPSALNPCEG DFRLQKLREA DSQDLKLSTI IDMLEGAFYG LDLLKLHSVT TKLVGRVDKL EEEVSKNLTK ENEQIKEDME EIRTEMNKRG KENCSENILD SMPDIRSALQ RDAAAAYAHP EYEERFLQEE TVSQQINSIE LLQTRPLALP EVVKSQRPLQ RQVHLRGRPA SQPTVIRGIT YYKAKVSEEE NDIEEQQDEF FSGDNGVDLL IEDQLLRHNG LMTSVTRRPA ATRQGHSTAV TSDLNARTAP WSSALPQPST SDPSIANHAS VGPTLQTTSV SPDPTRESVL QPSPQVPATT VAHTATQQPA APAPPAVSPR EALMEAMHTV PVPPTTVRTD SLGKDAPAGW GTTPASPTLS PEEEDDIRNV IGRCKDTLST ITGPTTQNTY GRNEGAWMKD PLAKDERIYV TNYYYGNTLV EFRNLENFKQ GRWSNSYKLP YSWIGTGHVV YNGAFYYNRA FTRNIIKYDL KQRYVAAWAM LHDVAYEEAT PWRWQGHSDV DFAVDENGLW LIYPALDDEG FSQEVIVLSK LNAADLSTQK ETTWRTGLRR NFYGNCFVIC GVLYAVDSYN QRNANISYAF DTHTNTQIVP RLLFENEYSY TTQIDYNPKD RLLYAWDNGH QVTYHVIFAY
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