Protein stum homolog (STUM)

About Protein stum homolog

Protein stum homolog (STUM) is a protein from Homo sapiens identified by UniProt accession Q69YW2, 141 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	Protein stum homolog
UniProt accession	Q69YW2
Gene	STUM
Organism	Homo sapiens
Length	141 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

mathematical ability · score 0.44
unipolar depression · score 0.29
PHF-tau measurement · score 0.28
metabolite measurement · score 0.05
total cholesterol measurement · score 0.04
drug use measurement · score 0.02
colorectal adenocarcinoma · score 0.02
astrocytoma · score 0.02
Ataxia-telangiectasia · score 0.02
colorectal cancer · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q69YW2-F1	alphafold	PREDICTED	59.56	—

Amino-acid sequence (141 residues)

MEPSHKDAET AAAAAAVAAA DPRGASSSSG VVVQVREKKG PLRAAIPYMP FPVAVICLFL NTFVPGLGTF VSAFTVLCGA RTDLPDRHVC CVFWLNIAAA LIQILTAIVM VGWIMSIFWG MDMVILAISQ GYKEQGIPQQ L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards