Transmembrane protein 200B (TMEM200B)

About Transmembrane protein 200B

Transmembrane protein 200B (TMEM200B) is a protein from Homo sapiens identified by UniProt accession Q69YZ2, 307 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.

Target properties

Protein name	Transmembrane protein 200B
UniProt accession	Q69YZ2
Gene	TMEM200B
Organism	Homo sapiens
Length	307 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (37)

Diseases linked to this target (Open Targets).

mean reticulocyte volume · score 0.19
mean corpuscular volume · score 0.17
reticulocyte count · score 0.16
reticulocyte measurement · score 0.14
mean corpuscular hemoglobin concentration · score 0.13
diastolic blood pressure · score 0.11
hypertension · score 0.08
wellbeing measurement · score 0.07
alcohol consumption measurement · score 0.07
hemoglobin measurement · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q69YZ2-F1	alphafold	PREDICTED	53.72	—

Amino-acid sequence (307 residues)

MTAGSPEECG EVRRSPEGRV SRLGRRLGRR RRPRSPPEPL RVRARLRLRS PSGAFAALGA LVVLVGMGIA VAGYWPHRAG APGSRAANAS SPQMSELRRE GRGGGRAHGP HERLRLLGPV IMGVGLFVFI CANTLLYENR DLETRRLRQG VLRAQALRPP DGPGWDCALL PSPGPRSPRA VGCAEPEIWD PSPRRGTSPV PSVRSLRSEP ANPRLGLPAL LNSYPLKGPG LPPPWGPRTQ TGHVIITVQP SGSCIEHSKS LDLGLGELLL GAPAARDCAH RSWPRLDRLS LGGYAKLGGG GDLGARV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards