Zinc finger protein 787 (ZNF787)

About Zinc finger protein 787

Zinc finger protein 787 (ZNF787) is a protein from Homo sapiens identified by UniProt accession Q6DD87, 382 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Protein name	Zinc finger protein 787
UniProt accession	Q6DD87
Gene	ZNF787
Organism	Homo sapiens
Length	382 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (14)

Diseases linked to this target (Open Targets).

sex hormone-binding globulin measurement · score 0.38
neurodegenerative disease · score 0.36
neuroinflammatory disorder · score 0.25
platelet count · score 0.19
Moebius syndrome · score 0.11
MODY · score 0.04
diabetes mellitus, permanent neonatal 4 · score 0.03
diabetes mellitus, transient neonatal, 3 · score 0.03
permanent neonatal diabetes mellitus 1 · score 0.03
juvenile dermatomyositis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6DD87-F1	alphafold	PREDICTED	64.05	—

Amino-acid sequence (382 residues)

MELREEAWSP GPLDSEDQQM ASHENPVDIL IMDDDDVPSW PPTKLSPPQS APPAGPPPRP RPPAPYICNE CGKSFSHWSK LTRHQRTHTG ERPNACADCG KTFSQSSHLV QHRRIHTGEK PYACLECGKR FSWSSNLMQH QRIHTGEKPY TCPDCGRSFT QSKSLAKHRR SHSGLKPFVC PRCGRGFSQP KSLARHLRLH PELSGPGVAA KVLAASVRRA KGPEEAVAAD GEIAIPVGDG EGIIVVGAPG EGAAAAAAMA GAGAKAAGPR SRRAPAPKPY VCLECGKGFG HGAGLLAHQR AQHGDGLGAA GGEEPAHICV ECGEGFVQGA ALRRHKKIHA VGAPSVCSSC GQSYYRAGGE EEDDDDEAAG GRCPECRGGE GR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards