Small ubiquitin-related modifier 4 (SUMO4)

About Small ubiquitin-related modifier 4

Small ubiquitin-related modifier 4 (SUMO4) is a protein from Homo sapiens identified by UniProt accession Q6EEV6, 95 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.

Target properties

Protein name	Small ubiquitin-related modifier 4
UniProt accession	Q6EEV6
Gene	SUMO4
Organism	Homo sapiens
Length	95 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (50)

Diseases linked to this target (Open Targets).

type 1 diabetes mellitus · score 0.34
Palmar Fibromatosis · score 0.14
Fasciitis · score 0.14
coronary artery disease · score 0.10
type 2 diabetes mellitus · score 0.09
BMI-adjusted hip circumference · score 0.09
axial length measurement · score 0.07
non-small cell lung carcinoma · score 0.07
neoplasm · score 0.04
diabetes mellitus · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6EEV6-F1	alphafold	PREDICTED	81.90	—

Amino-acid sequence (95 residues)

MANEKPTEEV KTENNNHINL KVAGQDGSVV QFKIKRQTPL SKLMKAYCEP RGLSVKQIRF RFGGQPISGT DKPAQLEMED EDTIDVFQQP TGGVY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards