About C-type lectin domain family 6 member A
C-type lectin domain family 6 member A (CLEC6A) is a protein
from Homo sapiens identified by UniProt accession
Q6EIG7, 209 residues long.
MolForge cross-references it against 0 known binders and
117 disease associations.
Target properties
| Protein name | C-type lectin domain family 6 member A |
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| UniProt accession | Q6EIG7 |
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| Gene | CLEC6A |
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| Organism | Homo sapiens |
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| Length | 209 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (117)
Diseases linked to this target (Open Targets).
- optic cup area measurement · score 0.31
- blood protein measurement · score 0.26
- squamous cell lung carcinoma · score 0.17
- viral load · score 0.16
- breast adenocarcinoma · score 0.16
- endometrial cancer · score 0.15
- head and neck squamous cell carcinoma · score 0.12
- gastric adenocarcinoma · score 0.11
- infection · score 0.09
- infect · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6EIG7-F1 | alphafold | PREDICTED | 91.27 | — |
Amino-acid sequence (209 residues)
MMQEQQPQST EKRGWLSLRL WSVAGISIAL LSACFIVSCV VTYHFTYGET GKRLSELHSY HSSLTCFSEG TKVPAWGCCP ASWKSFGSSC YFISSEEKVW SKSEQNCVEM GAHLVVFNTE AEQNFIVQQL NESFSYFLGL SDPQGNNNWQ WIDKTPYEKN VRFWHLGEPN HSAEQCASIV FWKPTGWGWN DVICETRRNS ICEMNKIYL
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