LHFPL tetraspan subfamily member 7 protein (LHFPL7)

About LHFPL tetraspan subfamily member 7 protein

LHFPL tetraspan subfamily member 7 protein (LHFPL7) is a protein from Homo sapiens identified by UniProt accession Q6ICI0, 200 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	LHFPL tetraspan subfamily member 7 protein
UniProt accession	Q6ICI0
Gene	LHFPL7
Organism	Homo sapiens
Length	200 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

sclerosing cholangitis · score 0.12
neoplasm · score 0.05
colorectal cancer · score 0.02
lymph node metastatic carcinoma · score 0.01
Crohn's disease · score 0.00
cancer · score 0.00
inflammatory bowel disease · score 0.00
adenomatous colon polyp · score 0.00
endometrial carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6ICI0-F1	alphafold	PREDICTED	81.77	—

Amino-acid sequence (200 residues)

MLSSVWVALG LSLTCTSAFS LISPAWFQTP TFSFGILTYC SWPQGNSWNQ SCVTFSSLED IPDFAWKVSA VMLLGGWLLL AFNAIFLLSW AVAPKGLCPR RSSVPMPGVQ AVAATAMIVG LLIFPIGLAS PFIKEVCEAS SMYYGGKCRL GWGYMTAILN AVLASLLPII SWPHTTKVQG RTIIFSSATE RIIFVPEMNK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards