Eukaryotic translation initiation factor 5A-1-like…

About Eukaryotic translation initiation factor 5A-1-like

Eukaryotic translation initiation factor 5A-1-like (EIF5AL1) is a protein from Homo sapiens identified by UniProt accession Q6IS14, 154 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

Target properties

Protein name	Eukaryotic translation initiation factor 5A-1-like
UniProt accession	Q6IS14
Gene	EIF5AL1
Organism	Homo sapiens
Length	154 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (18)

Diseases linked to this target (Open Targets).

lean body mass · score 0.22
fat body mass · score 0.19
whole body water mass · score 0.17
body height · score 0.16
grip strength measurement · score 0.16
sitting height measurement · score 0.15
appendicular lean mass · score 0.12
C-reactive protein measurement · score 0.07
platelet count · score 0.05
hemoglobin measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6IS14-F1	alphafold	PREDICTED	88.49	—

Amino-acid sequence (154 residues)

MADDLDFETG DAGASATFPM QCSALRKNGF VVLKGWPCKI VEMSASKTGK HGHAKVHLVG IDIFTGKKYE DICPSTHNMD VPNIKRNDFQ LIGIQDGYLS LLQDSGEVPE DLRLPEGDLG KEIEQKYDCG EEILITVLSA MTEEAAVAIK AMAK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Eukaryotic translation initiation factor 5A-1-like (EIF5AL1)