About 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 (OGFOD2) is a protein
from Homo sapiens identified by UniProt accession
Q6N063, 350 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 |
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| UniProt accession | Q6N063 |
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| Gene | OGFOD2 |
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| Organism | Homo sapiens |
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| Length | 350 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (42)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.13
- blood phosphate measurement · score 0.12
- intelligence · score 0.05
- type 2 diabetes mellitus · score 0.05
- schizophrenia · score 0.05
- body fat percentage · score 0.05
- eosinophil percentage of leukocytes · score 0.04
- calcium measurement · score 0.04
- self reported educational attainment · score 0.04
- macula measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6N063-F1 | alphafold | PREDICTED | 93.66 | — |
Amino-acid sequence (350 residues)
MATVGAPRHF CRCACFCTDN LYVARYGLHV RFRGEQQLRR DYGPILRSRG CVSAKDFQQL LAELEQEVER RQRLGQESAA RKALIASSYH PARPEVYDSL QDAALAPEFL AVTEYSVSPD ADLKGLLQRL ETVSEEKRIY RVPVFTAPFC QALLEELEHF EQSDMPKGRP NTMNNYGVLL HELGLDEPLM TPLRERFLQP LMALLYPDCG GGRLDSHRAF VVKYAPGQDL ELGCHYDNAE LTLNVALGKV FTGGALYFGG LFQAPTALTE PLEVEHVVGQ GVLHRGGQLH GARPLGTGER WNLVVWLRAS AVRNSLCPMC CREPDLVDDE GFGDGFTREE PATVDVCALT
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