About Ufm1-specific protease 1
Ufm1-specific protease 1 (UFSP1) is a protein
from Homo sapiens identified by UniProt accession
Q6NVU6, 218 residues long.
MolForge cross-references it against 0 known binders and
39 disease associations.
Target properties
| Protein name | Ufm1-specific protease 1 |
|---|
| UniProt accession | Q6NVU6 |
|---|
| Gene | UFSP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 218 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (39)
Diseases linked to this target (Open Targets).
- body height · score 0.22
- electrocardiography · score 0.22
- alkaline phosphatase measurement · score 0.21
- sex hormone-binding globulin measurement · score 0.21
- heart rate response to recovery post exercise · score 0.20
- resting heart rate · score 0.18
- neurodegenerative disease · score 0.17
- low density lipoprotein cholesterol measurement · score 0.16
- heart rate · score 0.16
- total cholesterol measurement · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6NVU6-F1 | alphafold | PREDICTED | 92.19 | — |
Amino-acid sequence (218 residues)
MEPLRDVHVG LSPPSRGPVR LALLSGHYLY YHYGCDGLDD RGWGCGYRTL QTLCSWPEGQ PAGVPGLAAV QAALEDMGDK PPGFRGSRDW IGCVEASLCL AHFGGPQGRL CHVPRGVGLH GELERLYSHF AGGGGPVMVG GDADARSKAL LGVCVGSGTE AYVLVLDPHY WGTPKSPSEL QAAGWVGWQE VSAAFDPNSF YNLCLTSLSS QQQQRTLD
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