RWD domain-containing protein 4 (RWDD4)

About RWD domain-containing protein 4

RWD domain-containing protein 4 (RWDD4) is a protein from Homo sapiens identified by UniProt accession Q6NW29, 188 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	RWD domain-containing protein 4
UniProt accession	Q6NW29
Gene	RWDD4
Organism	Homo sapiens
Length	188 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.54
monocyte count · score 0.06
systemic lupus erythematosus · score 0.05
response to radiation · score 0.03
Abnormality of the urinary system · score 0.03
Abnormal sperm morphology · score 0.01
neoplasm · score 0.00
breast ductal carcinoma in situ · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6NW29-F1	alphafold	PREDICTED	79.63	—

Amino-acid sequence (188 residues)

MSANEDQEME LEALRSIYEG DESFRELSPV SFQYRIGENG DPKAFLIEIS WTETYPQTPP ILSMNAFFNN TISSAVKQSI LAKLQEAVEA NLGTAMTYTL FEYAKDNKEQ FMENHNPINS ATSISNIISI ETPNTAPSSK KKDKKEQLSK AQKRKLADKT DHKGELPRGW NWVDVVKHLS KTGSKDDE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards