About STEAP family member 1B
STEAP family member 1B (STEAP1B) is a protein
from Homo sapiens identified by UniProt accession
Q6NZ63, 245 residues long.
MolForge cross-references it against 0 known binders and
48 disease associations.
Target properties
| Protein name | STEAP family member 1B |
|---|
| UniProt accession | Q6NZ63 |
|---|
| Gene | STEAP1B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 245 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (48)
Diseases linked to this target (Open Targets).
- platelet count · score 0.44
- lymphocyte count · score 0.41
- C-reactive protein measurement · score 0.40
- eosinophil count · score 0.38
- aspartate aminotransferase measurement · score 0.37
- leukocyte count · score 0.37
- serum albumin measurement · score 0.37
- asthma · score 0.36
- neurodegenerative disease · score 0.36
- neutrophil count · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6NZ63-F1 | alphafold | PREDICTED | 84.50 | — |
Amino-acid sequence (245 residues)
MESRKDITNQ EEIWKMKPRR NLEDNDYLQT AHADEFDCPS ELQHAQELFP QWHLPIKIAA VMASLTFLYT LLREVIHPLA TSHQQYFYKI PILVINKVLP MVSITLLALV YLPGVIAAIV QVHNGTKYKK FPHWLDKWML TRKQFGLLSL FFAVLHAIYT LSYAMRRSYR YKLLNWAYQQ VQQNKEDAWI EHDVWRMEIY VSLGIVGLAI LALLAVTSIP SVSDSLTWRE FHYIQVHGRI NFLTL
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