About Protein TEX261
Protein TEX261 (TEX261) is a protein
from Homo sapiens identified by UniProt accession
Q6UWH6, 196 residues long.
MolForge cross-references it against 0 known binders and
25 disease associations.
Target properties
| Protein name | Protein TEX261 |
|---|
| UniProt accession | Q6UWH6 |
|---|
| Gene | TEX261 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 196 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (25)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.38
- serum metabolite measurement · score 0.31
- congenital analbuminemia · score 0.04
- hemoglobin E-beta-thalassemia syndrome · score 0.04
- Hemolytic anemia due to red cell pyruvate kinase deficiency · score 0.04
- refractory celiac disease · score 0.03
- congenital dyserythropoietic anemia type 4 · score 0.03
- Congenital dyserythropoietic anemia type IV · score 0.03
- chylomicron retention disease · score 0.03
- IRIDA syndrome · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6UWH6-F1 | alphafold | PREDICTED | 82.35 | — |
Amino-acid sequence (196 residues)
MWFMYLLSWL SLFIQVAFIT LAVAAGLYYL AELIEEYTVA TSRIIKYMIW FSTAVLIGLY VFERFPTSMI GVGLFTNLVY FGLLQTFPFI MLTSPNFILS CGLVVVNHYL AFQFFAEEYY PFSEVLAYFT FCLWIIPFAF FVSLSAGENV LPSTMQPGDD VVSNYFTKGK RGKRLGILVV FSFIKEAILP SRQKIY
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