About Ly6/PLAUR domain-containing protein 5
Ly6/PLAUR domain-containing protein 5 (LYPD5) is a protein
from Homo sapiens identified by UniProt accession
Q6UWN5, 251 residues long.
MolForge cross-references it against 0 known binders and
54 disease associations.
Target properties
| Protein name | Ly6/PLAUR domain-containing protein 5 |
|---|
| UniProt accession | Q6UWN5 |
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| Gene | LYPD5 |
|---|
| Organism | Homo sapiens |
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| Length | 251 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (54)
Diseases linked to this target (Open Targets).
- reading · score 0.25
- Red cell distribution width · score 0.21
- monocyte count · score 0.19
- heel bone mineral density · score 0.11
- urokinase plasminogen activator surface receptor measurement · score 0.07
- breast carcinoma · score 0.07
- bone density · score 0.06
- estrogen-receptor negative breast cancer · score 0.05
- platelet crit · score 0.03
- lymphocyte count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6UWN5-F1 | alphafold | PREDICTED | 83.99 | — |
Amino-acid sequence (251 residues)
MAMGVPRVIL LCLFGAALCL TGSQALQCYS FEHTYFGPFD LRAMKLPSIS CPHECFEAIL SLDTGYRAPV TLVRKGCWTG PPAGQTQSNA DALPPDYSVV RGCTTDKCNA HLMTHDALPN LSQAPDPPTL SGAECYACIG VHQDDCAIGR SRRVQCHQDQ TACFQGNGRM TVGNFSVPVY IRTCHRPSCT TEGTTSPWTA IDLQGSCCEG YLCNRKSMTQ PFTSASATTP PRALQVLALL LPVLLLVGLS A
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