C-X-C motif chemokine 17 (CXCL17)

About C-X-C motif chemokine 17

C-X-C motif chemokine 17 (CXCL17) is a protein from Homo sapiens identified by UniProt accession Q6UXB2, 119 residues long. MolForge cross-references it against 0 known binders and 110 disease associations.

Target properties

Protein name	C-X-C motif chemokine 17
UniProt accession	Q6UXB2
Gene	CXCL17
Organism	Homo sapiens
Length	119 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (110)

Diseases linked to this target (Open Targets).

testosterone measurement · score 0.16
neoplasm · score 0.11
hepatocellular carcinoma · score 0.09
influenza · score 0.07
COVID-19 · score 0.07
lung adenocarcinoma · score 0.06
cancer · score 0.05
gonorrhea · score 0.05
pulmonary tuberculosis · score 0.05
colon carcinoma · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UXB2-F1	alphafold	PREDICTED	59.64	—

Amino-acid sequence (119 residues)

MKVLISSLLL LLPLMLMSMV SSSLNPGVAR GHRDRGQASR RWLQEGGQEC ECKDWFLRAP RRKFMTVSGL PKKQCPCDHF KGNVKKTRHQ RHHRKPNKHS RACQQFLKQC QLRSFALPL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards