CMRF35-like molecule 9 (CD300LG)

About CMRF35-like molecule 9

CMRF35-like molecule 9 (CD300LG) is a protein from Homo sapiens identified by UniProt accession Q6UXG3, 332 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.

Target properties

Protein name	CMRF35-like molecule 9
UniProt accession	Q6UXG3
Gene	CD300LG
Organism	Homo sapiens
Length	332 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (53)

Diseases linked to this target (Open Targets).

high density lipoprotein cholesterol measurement · score 0.51
triglyceride measurement · score 0.49
lymphocyte count · score 0.38
eosinophil count · score 0.38
triglyceride:HDL cholesterol ratio · score 0.37
apolipoprotein A 1 measurement · score 0.37
total cholesterol measurement · score 0.34
Red cell distribution width · score 0.30
metabolic syndrome · score 0.26
lipoprotein measurement · score 0.23

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UXG3-F1	alphafold	PREDICTED	68.74	—

Amino-acid sequence (332 residues)

MRLLVLLWGC LLLPGYEALE GPEEISGFEG DTVSLQCTYR EELRDHRKYW CRKGGILFSR CSGTIYAEEE GQETMKGRVS IRDSRQELSL IVTLWNLTLQ DAGEYWCGVE KRGPDESLLI SLFVFPGPCC PPSPSPTFQP LATTRLQPKA KAQQTQPPGL TSPGLYPAAT TAKQGKTGAE APPLPGTSQY GHERTSQYTG TSPHPATSPP AGSSRPPMQL DSTSAEDTSP ALSSGSSKPR VSIPMVRILA PVLVLLSLLS AAGLIAFCSH LLLWRKEAQQ ATETQRNEKF CLSRLTAEEK EAPSQAPEGD VISMPPLHTS EEELGFSKFV SA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards