About Collagen and calcium-binding EGF domain-containing protein 1
Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1) is a protein
from Homo sapiens identified by UniProt accession
Q6UXH8, 406 residues long.
MolForge cross-references it against 0 known binders and
262 disease associations.
Target properties
| Protein name | Collagen and calcium-binding EGF domain-containing protein 1 |
|---|
| UniProt accession | Q6UXH8 |
|---|
| Gene | CCBE1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 406 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (262)
Diseases linked to this target (Open Targets).
- Hennekam syndrome · score 0.77
- mean corpuscular volume · score 0.51
- platelet count · score 0.50
- reticulocyte count · score 0.48
- mean corpuscular hemoglobin · score 0.48
- mean platelet volume · score 0.47
- mean corpuscular hemoglobin concentration · score 0.47
- appendicular lean mass · score 0.47
- reticulocyte measurement · score 0.45
- serum albumin measurement · score 0.44
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6UXH8-F1 | alphafold | PREDICTED | 64.87 | — |
Amino-acid sequence (406 residues)
MVPPPPSRGG AARGQLGRSL GPLLLLLALG HTWTYREEPE DGDREICSES KIATTKYPCL KSSGELTTCY RKKCCKGYKF VLGQCIPEDY DVCAEAPCEQ QCTDNFGRVL CTCYPGYRYD RERHRKREKP YCLDIDECAS SNGTLCAHIC INTLGSYRCE CREGYIREDD GKTCTRGDKY PNDTGHEKSE NMVKAGTCCA TCKEFYQMKQ TVLQLKQKIA LLPNNAADLG KYITGDKVLA SNTYLPGPPG LPGGQGPPGS PGPKGSPGFP GMPGPPGQPG PRGSMGPMGP SPDLSHIKQG RRGPVGPPGA PGRDGSKGER GAPGPRGSPG PPGSFDFLLL MLADIRNDIT ELQEKVFGHR THSSAEEFPL PQEFPSYPEA MDLGSGDDHP RRTETRDLRA PRDFYP
Explore Collagen and calcium-binding EGF domain-containing protein 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets