Trem-like transcript 4 protein (TREML4)

About Trem-like transcript 4 protein

Trem-like transcript 4 protein (TREML4) is a protein from Homo sapiens identified by UniProt accession Q6UXN2, 200 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.

Target properties

Protein name	Trem-like transcript 4 protein
UniProt accession	Q6UXN2
Gene	TREML4
Organism	Homo sapiens
Length	200 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (45)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.27
bone density · score 0.08
urate measurement · score 0.08
atherosclerosis · score 0.04
monocyte count · score 0.04
coronary artery disease · score 0.03
breast carcinoma · score 0.03
influenza · score 0.02
Sepsis · score 0.02
infection · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UXN2-F1	alphafold	PREDICTED	76.37	—

Amino-acid sequence (200 residues)

MAWGGVHTCC FHLCCCCSWP QGAVPEELHK HPGQTLLLQC QYSPKRGPYQ PKSWCQQTSP SRCTLLVTSS KPWTAVQKSH YTIWDKPNAG FFNITMIQLT QNDSGFYWCG IYNASENIIT VLRNISLVVS PAPTTSPMWT LPWLPTSTVL ITSPEGTSGH PSINGSETRK SRAPACLGSG GPRFLVLVLC GLLLAKGLML

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards