About C-type lectin domain family 19 member A
C-type lectin domain family 19 member A (CLEC19A) is a protein
from Homo sapiens identified by UniProt accession
Q6UXS0, 186 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | C-type lectin domain family 19 member A |
|---|
| UniProt accession | Q6UXS0 |
|---|
| Gene | CLEC19A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 186 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (22)
Diseases linked to this target (Open Targets).
- periodontal measurement · score 0.23
- self reported educational attainment · score 0.15
- body height · score 0.14
- Parkinson disease · score 0.12
- diet measurement · score 0.12
- forced expiratory volume · score 0.11
- appendicular lean mass · score 0.11
- vital capacity · score 0.10
- sitting height measurement · score 0.10
- eosinophil percentage of leukocytes · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6UXS0-F1 | alphafold | PREDICTED | 85.06 | — |
Amino-acid sequence (186 residues)
MQRWTLWAAA FLTLHSAQAF PQTDISISPA LPELPLPSLC PLFWMEFKGH CYRFFPLNKT WAEADLYCSE FSVGRKSAKL ASIHSWEENV FVYDLVNSCV PGIPADVWTG LHDHRQEGQF EWTDGSSYDY SYWDGSQPDD GVHADPEEED CVQIWYRPTS ALRSWNDNTC SRKFPFVCKI PSLTIH
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