About Germ cell-specific gene 1-like protein
Germ cell-specific gene 1-like protein (GSG1L) is a protein
from Homo sapiens identified by UniProt accession
Q6UXU4, 331 residues long.
MolForge cross-references it against 0 known binders and
50 disease associations.
Target properties
| Protein name | Germ cell-specific gene 1-like protein |
|---|
| UniProt accession | Q6UXU4 |
|---|
| Gene | GSG1L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 331 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (50)
Diseases linked to this target (Open Targets).
- mastiha supplement exposure measurement · score 0.33
- hemoglobin measurement · score 0.33
- visual perception measurement · score 0.32
- neurofibrillary tangles measurement · score 0.32
- temporal horn of lateral ventricle volume measurement · score 0.30
- gut microbiome measurement · score 0.27
- bone density · score 0.27
- metabolite measurement · score 0.25
- glucuronate measurement · score 0.10
- attention deficit hyperactivity disorder · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6UXU4-F1 | alphafold | PREDICTED | 71.62 | — |
Amino-acid sequence (331 residues)
MKTSRRGRAL LAVALNLLAL LFATTAFLTT HWCQGTQRVP KPGCGQGGRA NCPNSGANAT ANGTAAPAAA AAAATASGNG PPGGALYSWE TGDDRFLFRN FHTGIWYSCE EELSGLGEKC RSFIDLAPAS EKGVLWLSVV SEVLYILLLV VGFSLMCLEL FHSSNVIDGL KLNAFAAVFT VLSGLLGMVA HMMYTQVFQV TVSLGPEDWR PHSWDYGWSF CLAWGSFTCC MAASVTTLNS YTKTVIEFRH KRKVFEQGYR EEPTFIDPEA IKYFRERMEK RDGSEEDFHL DCRHERYPAR HQPHMADSWP RSSAQEAPEL NRQCWVLGHW V
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