About Cilia- and flagella-associated protein 299
Cilia- and flagella-associated protein 299 (CFAP299) is a protein
from Homo sapiens identified by UniProt accession
Q6V702, 233 residues long.
MolForge cross-references it against 0 known binders and
91 disease associations.
Target properties
| Protein name | Cilia- and flagella-associated protein 299 |
|---|
| UniProt accession | Q6V702 |
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| Gene | CFAP299 |
|---|
| Organism | Homo sapiens |
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| Length | 233 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (91)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.46
- body height · score 0.43
- appendicular lean mass · score 0.40
- hair color · score 0.39
- fat body mass · score 0.37
- sitting height measurement · score 0.35
- heel bone mineral density · score 0.31
- base metabolic rate measurement · score 0.30
- whole body water mass · score 0.30
- forced expiratory volume · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6V702-F1 | alphafold | PREDICTED | 87.26 | — |
Amino-acid sequence (233 residues)
MDQEEGLKAL DNIVTQFNAY EDFLDSQITT VDLYYLEDET LARQLVELGY RGTGERVKRE DFEARKAAIE IARLAERAQQ KTLTSAGKDL QDNFLTALAM REEDNRSGKL SSVIFIRDRN SHGQEISGYI DYAHRLKTED FEVYFTGKKR LLPRPTDISF YNWDADIAVS NSSPNYQVIA DNPEGLLFRY KRDRKILNVD PKAQPGDNST RITILTELYV QAVIFDHISR RKT
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