About Achaete-scute homolog 4
Achaete-scute homolog 4 (ASCL4) is a protein
from Homo sapiens identified by UniProt accession
Q6XD76, 172 residues long.
MolForge cross-references it against 0 known binders and
37 disease associations.
Target properties
| Protein name | Achaete-scute homolog 4 |
|---|
| UniProt accession | Q6XD76 |
|---|
| Gene | ASCL4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 172 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (37)
Diseases linked to this target (Open Targets).
- body mass index · score 0.27
- daytime rest measurement · score 0.21
- neutrophil percentage of leukocytes · score 0.15
- body fat percentage · score 0.07
- body weight · score 0.07
- balding measurement · score 0.05
- transient myeloproliferative syndrome · score 0.04
- neutrophil immunodeficiency syndrome · score 0.04
- hair shape measurement · score 0.04
- body height · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6XD76-F1 | alphafold | PREDICTED | 70.34 | — |
Amino-acid sequence (172 residues)
METRKPAERL ALPYSLRTAP LGVPGTLPGL PRRDPLRVAL RLDAACWEWA RSGCARGWQY LPVPLDSAFE PAFLRKRNER ERQRVRCVNE GYARLRDHLP RELADKRLSK VETLRAAIDY IKHLQELLER QAWGLEGAAG AVPQRRAECN SDGESKASSA PSPSSEPEEG GS
Explore Achaete-scute homolog 4 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets