Transcription factor LBX2 (LBX2)

About Transcription factor LBX2

Transcription factor LBX2 (LBX2) is a protein from Homo sapiens identified by UniProt accession Q6XYB7, 198 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.

Target properties

Protein name	Transcription factor LBX2
UniProt accession	Q6XYB7
Gene	LBX2
Organism	Homo sapiens
Length	198 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (55)

Diseases linked to this target (Open Targets).

platelet count · score 0.17
platelet crit · score 0.17
serum urea measurement · score 0.12
gonorrhea · score 0.09
neoplasm · score 0.08
lung adenocarcinoma · score 0.08
IGF-1 measurement · score 0.08
Miyoshi myopathy · score 0.07
acute myeloid leukemia · score 0.07
body height · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6XYB7-F1	alphafold	PREDICTED	74.46	—

Amino-acid sequence (198 residues)

MNSGREPRTP RTLLSIADIL APRMVPRAPS APQLPESGPG PTSPLCALEE LTSKTFRGLD ARALQPSEGR AGPDALGPGP FGRKRRKSRT AFTAQQVLEL ERRFVFQKYL APSERDGLAT RLGLANAQVV TWFQNRRAKL KRDVEEMRAD VASLRALSPE VLCSLALPEG APDPGLCLGP AGPDSRPHLS DEEIQVDD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards