About Zinc transporter ZIP5
Zinc transporter ZIP5 (SLC39A5) is a protein
from Homo sapiens identified by UniProt accession
Q6ZMH5, 540 residues long.
MolForge cross-references it against 0 known binders and
89 disease associations.
Target properties
| Protein name | Zinc transporter ZIP5 |
|---|
| UniProt accession | Q6ZMH5 |
|---|
| Gene | SLC39A5 |
|---|
| Organism | Homo sapiens |
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| Length | 540 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (89)
Diseases linked to this target (Open Targets).
- Myopia · score 0.64
- alkaline phosphatase measurement · score 0.52
- acute myeloid leukemia · score 0.11
- Barrett's esophagus · score 0.08
- Hyperlipoproteinemia type 1 · score 0.06
- body height · score 0.05
- hepatocellular carcinoma · score 0.05
- forced expiratory volume · score 0.05
- Inguinal hernia · score 0.05
- esophageal adenocarcinoma · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6ZMH5-F1 | alphafold | PREDICTED | 67.28 | — |
Amino-acid sequence (540 residues)
MMGSPVSHLL AGFCVWVVLG WVGGSVPNLG PAEQEQNHYL AQLFGLYGEN GTLTAGGLAR LLHSLGLGRV QGLRLGQHGP LTGRAASPAA DNSTHRPQNP ELSVDVWAGM PLGPSGWGDL EESKAPHLPR GPAPSGLDLL HRLLLLDHSL ADHLNEDCLN GSQLLVNFGL SPAAPLTPRQ FALLCPALLY QIDSRVCIGA PAPAPPGDLL SALLQSALAV LLLSLPSPLS LLLLRLLGPR LLRPLLGFLG ALAVGTLCGD ALLHLLPHAQ EGRHAGPGGL PEKDLGPGLS VLGGLFLLFV LENMLGLLRH RGLRPRCCRR KRRNLETRNL DPENGSGMAL QPLQAAPEPG AQGQREKNSQ HPPALAPPGH QGHSHGHQGG TDITWMVLLG DGLHNLTDGL AIGAAFSDGF SSGLSTTLAV FCHELPHELG DFAMLLQSGL SFRRLLLLSL VSGALGLGGA VLGVGLSLGP VPLTPWVFGV TAGVFLYVAL VDMLPALLRP PEPLPTPHVL LQGLGLLLGG GLMLAITLLE ERLLPVTTEG
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